- off one’s nut
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1. mod. crazy; out of one’s head.□ Shut up! You’re off your nut!□ Don’t pay any attention to her. She’s off her nut.2. mod. alcohol intoxicated.□ Those guys are really off their nuts!□ She just sat there and got more and more off her nut.
Dictionary of American slang and colloquial expressions. 2015.